Search results for "Purpureocillium lilacinum"

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Insect-associated bacteria assemble the antifungal butenolide gladiofungin by non-canonical polyketide chain termination

2020

Abstract Genome mining of one of the protective symbionts (Burkholderia gladioli) of the invasive beetle Lagria villosa revealed a cryptic gene cluster that codes for the biosynthesis of a novel antifungal polyketide with a glutarimide pharmacophore. Targeted gene inactivation, metabolic profiling, and bioassays led to the discovery of the gladiofungins as previously‐overlooked components of the antimicrobial armory of the beetle symbiont, which are highly active against the entomopathogenic fungus Purpureocillium lilacinum. By mutational analyses, isotope labeling, and computational analyses of the modular polyketide synthase, we found that the rare butenolide moiety of gladiofungins deriv…

Burkholderia gladioliAntifungal AgentsBurkholderianatural productsantifungal compoundsMicrobial Sensitivity TestsBiosynthesis010402 general chemistry01 natural sciencesCatalysisPurpureocillium lilacinumPolyketide4-ButyrolactonePolyketide synthasegenome miningGene clusterAnimalsButenolidebiology010405 organic chemistryCommunicationGeneral Chemistrybiology.organism_classificationCommunications0104 chemical sciencesColeopteraBiochemistryPolyketidesHypocrealesbiology.proteinLactimidomycinPharmacophore
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Evaluation of antifungal activity of three essential oils against selected isolates of Penicillium, Purpureocillium and Acremonium

2018

Storage is a critical process of food production because incorrect conditions during this process lead to the growth of economic costs caused by material loss. It is important to maintain adequate microbiological purity of storage areas. The development of microbes present in warehouses may lead to secondary contamination of stored materials and reduce their quality. The aim of the study was to evaluate the effect of essential oils on the growth of Acremonium strictum , Penicillium citrinum, Penicillium expansum and Purpureocillium lilacinum . Fungal strains were isolated from the food warehouse. Studies on the influence of selected mix of phenolic substances were performed using three comm…

EcologybiologyAcremoniumEcological ModelingGeography Planning and DevelopmentAcremonium strictumbiology.organism_classificationFungicidechemistry.chemical_compoundPurpureocillium lilacinumMinimum inhibitory concentrationchemistryPenicilliumPenicillium citrinumFood sciencePenicillium expansumEcology Evolution Behavior and SystematicsEcological Questions
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